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ATM, ATR, CHK1, CHK2 and WEE1 inhibitors in cancer and cancer stem cells
DNA inevitably undergoes a high number of damages throughout the cell cycle. To preserve the integrity of the genome, cells have developed a complex enzymatic machinery aimed at sensing and repairing DNA lesions, pausing the cell cycle to provide more time to repair, or induce apoptosis if damages a...
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| Publicado no: | Medchemcomm |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072143/ https://ncbi.nlm.nih.gov/pubmed/30108746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00439c |
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