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Targeting the ATR-CHK1 Axis in Cancer Therapy
Targeting the DNA damage response (DDR) is a new therapeutic approach in cancer that shows great promise for tumour selectivity. Key components of the DDR are the ataxia telangiectasia mutated and Rad3 related (ATR) and checkpoint kinase 1 (CHK1) kinases. This review article describes the role of AT...
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| Udgivet i: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5447951/ https://ncbi.nlm.nih.gov/pubmed/28448462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9050041 |
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