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Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy
The ataxia telangiectasia mutated serine/threonine kinase (ATM)/checkpoint kinase 2 (CHEK2, best known as CHK2) and the ATM and Rad3-related serine/threonine kinase (ATR)/CHEK1 (best known as CHK1) cascades are the 2 major signaling pathways driving the DNA damage response (DDR), a network of proces...
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Publicado no: | Mol Cell Oncol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905354/ https://ncbi.nlm.nih.gov/pubmed/27308506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1012976 |
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