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Trial watch – inhibiting PARP enzymes for anticancer therapy

Poly(ADP-ribose) polymerases (PARPs) are a members of family of enzymes that catalyze poly(ADP-ribosyl)ation (PARylation) and/or mono(ADP-ribosyl)ation (MARylation), two post-translational protein modifications involved in crucial cellular processes including (but not limited to) the DNA damage resp...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Sistigu, Antonella, Manic, Gwenola, Obrist, Florine, Vitale, Ilio
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905370/
https://ncbi.nlm.nih.gov/pubmed/27308587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1053594
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