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Trial Watch: Proteasomal inhibitors for anticancer therapy

The so-called “ubiquitin-proteasome system” (UPS) is a multicomponent molecular apparatus that catalyzes the covalent attachment of several copies of the small protein ubiquitin to other proteins that are generally (but not always) destined to proteasomal degradation. This enzymatic cascade is cruci...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Obrist, Florine, Manic, Gwenola, Kroemer, Guido, Vitale, Ilio, Galluzzi, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904962/
https://ncbi.nlm.nih.gov/pubmed/27308423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.974463
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