Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer

Small cell lung cancer (SCLC) is a difficult to treat subtype of lung cancer. One of the hallmarks of SCLC is its almost uniform chemotherapy sensitivity. However, chemotherapy response is typically transient and patients frequently succumb to SCLC within a year following diagnosis. We performed a t...

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Vydáno v:Sci Rep
Hlavní autoři: Doerr, Fabian, George, Julie, Schmitt, Anna, Beleggia, Filippo, Rehkämper, Tim, Hermann, Sarah, Walter, Vonn, Weber, Jean-Philip, Thomas, Roman K., Wittersheim, Maike, Büttner, Reinhard, Persigehl, Thorsten, Reinhardt, H. Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686113/
https://ncbi.nlm.nih.gov/pubmed/29138515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15840-5
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