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Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer

Small cell lung cancer (SCLC) is a difficult to treat subtype of lung cancer. One of the hallmarks of SCLC is its almost uniform chemotherapy sensitivity. However, chemotherapy response is typically transient and patients frequently succumb to SCLC within a year following diagnosis. We performed a t...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Doerr, Fabian, George, Julie, Schmitt, Anna, Beleggia, Filippo, Rehkämper, Tim, Hermann, Sarah, Walter, Vonn, Weber, Jean-Philip, Thomas, Roman K., Wittersheim, Maike, Büttner, Reinhard, Persigehl, Thorsten, Reinhardt, H. Christian
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686113/
https://ncbi.nlm.nih.gov/pubmed/29138515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15840-5
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