Characterization of Structurally Novel G Protein Biased CB1 Agonists: Implications for Drug Development

The human cannabinoid subtype 1 receptor (hCB(1)R) is highly expressed in the CNS and serves as a therapeutic target for endogenous ligands as well as plant-derived and synthetic cannabinoids. Unfortunately, acute use of hCB(1)R agonists produces unwanted psychotropic effects and chronic administrat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacol Res
Prif Awduron: Ford, Benjamin M., Franks, Lirit N., Tai, Sherrica, Fantegrossi, William E., Stahl, Edward L., Berquist, Michael D., Cabanlong, Christian V., Wilson, Catheryn D., Penthala, Narsimha R., Crooks, Peter A., Prather, Paul L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849406/
https://ncbi.nlm.nih.gov/pubmed/28838808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.08.008
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