Characterization of Structurally Novel G Protein Biased CB1 Agonists: Implications for Drug Development

The human cannabinoid subtype 1 receptor (hCB(1)R) is highly expressed in the CNS and serves as a therapeutic target for endogenous ligands as well as plant-derived and synthetic cannabinoids. Unfortunately, acute use of hCB(1)R agonists produces unwanted psychotropic effects and chronic administrat...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Ford, Benjamin M., Franks, Lirit N., Tai, Sherrica, Fantegrossi, William E., Stahl, Edward L., Berquist, Michael D., Cabanlong, Christian V., Wilson, Catheryn D., Penthala, Narsimha R., Crooks, Peter A., Prather, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849406/
https://ncbi.nlm.nih.gov/pubmed/28838808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.08.008
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