Reduced Tolerance and Asymmetrical Crosstolerance to Effects of the Indole Quinuclidinone Analog PNR-4-20, a G Protein–Biased Cannabinoid 1 Receptor Agonist in Mice: Comparisons with Δ(9)-Tetrahydrocannabinol and JWH-018

Lignende værker

• Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors
  af: Rajasekaran, Maheswari, et al.
  Udgivet: (2013)
• Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole Quinuclidine analogues
  af: Franks, Lirit N., et al.
  Udgivet: (2014)
• Differential Drug–Drug Interactions of the Synthetic Cannabinoids JWH-018 and JWH-073: Implications for Drug Abuse Liability and Pain Therapy
  af: Brents, Lisa K., et al.
  Udgivet: (2013)
• In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ(9)-THC in mice: Inhalation versus intraperitoneal injection
  af: Marshell, R., et al.
  Udgivet: (2014)
• Repeated administration of phytocannabinoid Δ(9)-THC or synthetic cannabinoids JWH-018 and JWH-073 induces tolerance to hypothermia but not locomotor suppression in mice, and reduces CB1 receptor expression and function in a brain region-specific manner
  af: Tai, S, et al.
  Udgivet: (2015)