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The tamoxifen derivative ridaifen-B is a high affinity selective CB(2) receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects
Selective estrogen receptor modulators (SERMs) target estrogen receptors (ERs) to treat breast cancer and osteoporosis. Several SERMs exhibit anti-cancer activity not related to ERs. To discover novel anti-cancer drugs acting via ER-independent mechanisms, derivatives of the SERM tamoxifen, known as...
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| Publicado no: | Toxicol Appl Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487498/ https://ncbi.nlm.nih.gov/pubmed/29906493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2018.06.009 |
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