Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice

Convulsant effects of abused synthetic cannabinoid (SCB) drugs have been reported in humans and laboratory animals, but the mechanism of these effects is not known. We compared convulsant effects of partial CB1R agonist ∆(9)-tetrahydrocannabinol (THC), full CB1R agonist SCBs JWH-018 and 5F-AB-PINACA...

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Veröffentlicht in:J Pharmacol Exp Ther
Hauptverfasser: Wilson, Catheryn D., Tai, Sherrica, Ewing, Laura, Crane, Jasmine, Lockhart, Taylor, Fujiwara, Ryochi, Radominska-Pandya, Anna, Fantegrossi, William E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2019
Schlagworte:
Behavioral Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323622/
https://ncbi.nlm.nih.gov/pubmed/30420360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.251157
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