Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice

Convulsant effects of abused synthetic cannabinoid (SCB) drugs have been reported in humans and laboratory animals, but the mechanism of these effects is not known. We compared convulsant effects of partial CB1R agonist ∆(9)-tetrahydrocannabinol (THC), full CB1R agonist SCBs JWH-018 and 5F-AB-PINACA...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Wilson, Catheryn D., Tai, Sherrica, Ewing, Laura, Crane, Jasmine, Lockhart, Taylor, Fujiwara, Ryochi, Radominska-Pandya, Anna, Fantegrossi, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Behavioral Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323622/
https://ncbi.nlm.nih.gov/pubmed/30420360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.251157
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