Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants

Synthetic cannabinoids (SCBs), synonymous with ‘K2’, ‘Spice’ or ‘synthetic marijuana’, are psychoactive drugs of abuse that frequently result in clinical effects and toxicity more severe than those classically associated with Δ(9)-tetrahydrocannabinol such as extreme agitation, hallucinations, supra...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Patton, Amy L., Seely, Kathryn A., Yarbrough, Azure L., Fantegrossi, William, James, Laura P., McCain, Keith R., Fujiwara, Ryoichi, Prather, Paul L., Moran, Jeffery H., Radominska-Pandya, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425723/
https://ncbi.nlm.nih.gov/pubmed/29522717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.03.028
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