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A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors

Recently, hydroxylated metabolites of JWH-018, a synthetic cannabinoid found in many K2/Spice preparations, have been shown to retain affinity and activity for cannabinoid type 1 receptors (CB1Rs). The activity of glucuronidated metabolites of JWH-018 is not known; hence this study investigated the...

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Bibliografski detalji
Glavni autori: Seely, Kathryn A., Brents, Lisa K., Radominska-Pandya, Anna, Endres, Gregory W., Keyes, Gregory S., Moran, Jeffery H., Prather, Paul L.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921679/
https://ncbi.nlm.nih.gov/pubmed/22404317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3000472
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