Natural (∆(9)-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB(1) receptor

Natural cannabinoids and their synthetic substitutes are the most widely used recreational drugs. Numerous clinical cases describe acute toxic symptoms and neurological consequences following inhalation of the mixture of synthetic cannabinoids known as “Spice.” Here we report that an intraperitoneal...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Malyshevskaya, Olga, Aritake, Kosuke, Kaushik, Mahesh K., Uchiyama, Nahoko, Cherasse, Yoan, Kikura-Hanajiri, Ruri, Urade, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585372/
https://ncbi.nlm.nih.gov/pubmed/28874764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10447-2
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