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Enantioselective Intermolecular [2+2] Photocycloaddition Reaction of Cyclic Enones and Its Application in a Synthesis of (−)-Grandisol

[Image: see text] The intermolecular [2+2] photocycloaddition of typical cyclic α,β-unsaturated enones, such as 2-cyclohexenone, with olefins was performed in moderate to good yields (42–82%) and with high enantioselectivity (82%–96% ee). An unusual substitution pattern at the chiral oxazaborolidine...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Poplata, Saner, Bach, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849358/
https://ncbi.nlm.nih.gov/pubmed/29458250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b01011
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