Dietary Linoleic Acid Lowering Reduces Lipopolysaccharide-Induced Increase in Brain Arachidonic Acid Metabolism

Linoleic acid (LA, 18:2n-6) is a precursor to arachidonic acid (AA, 20:4n-6), which can be converted by brain lipoxygenase and cyclooxygenase (COX) enzymes into various lipid mediators involved in the regulation of brain immunity. Brain AA metabolism is activated in rodents by the bacterial endotoxi...

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Bibliographic Details
Published in:Mol Neurobiol
Main Authors: Taha, Ameer Y., Blanchard, Helene C., Cheon, Yewon, Ramadan, Epolia, Chen, Mei, Chang, Lisa, Rapoport, Stanley I.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843819/
https://ncbi.nlm.nih.gov/pubmed/27339880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-9968-1
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