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Dietary Linoleic Acid Lowering Reduces Lipopolysaccharide-Induced Increase in Brain Arachidonic Acid Metabolism

Linoleic acid (LA, 18:2n-6) is a precursor to arachidonic acid (AA, 20:4n-6), which can be converted by brain lipoxygenase and cyclooxygenase (COX) enzymes into various lipid mediators involved in the regulation of brain immunity. Brain AA metabolism is activated in rodents by the bacterial endotoxi...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Taha, Ameer Y., Blanchard, Helene C., Cheon, Yewon, Ramadan, Epolia, Chen, Mei, Chang, Lisa, Rapoport, Stanley I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843819/
https://ncbi.nlm.nih.gov/pubmed/27339880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-9968-1
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