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Dietary Linoleic Acid Lowering Reduces Lipopolysaccharide-Induced Increase in Brain Arachidonic Acid Metabolism

Linoleic acid (LA, 18:2n-6) is a precursor to arachidonic acid (AA, 20:4n-6), which can be converted by brain lipoxygenase and cyclooxygenase (COX) enzymes into various lipid mediators involved in the regulation of brain immunity. Brain AA metabolism is activated in rodents by the bacterial endotoxi...

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Bibliografske podrobnosti
izdano v:Mol Neurobiol
Main Authors: Taha, Ameer Y., Blanchard, Helene C., Cheon, Yewon, Ramadan, Epolia, Chen, Mei, Chang, Lisa, Rapoport, Stanley I.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843819/
https://ncbi.nlm.nih.gov/pubmed/27339880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-9968-1
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