Chronic Valproate Treatment Blocks D(2)-like Receptor-Mediated Brain Signaling via Arachidonic Acid in Rats

BACKGROUND AND OBJECTIVE: Hyperdopaminergic signaling and an upregulated brain arachidonic acid (AA) cascade may contribute to bipolar disorder (BD). Lithium and carbamazepine, FDA-approved for the treatment of BD, attenuate brain dopaminergic D(2)-like (D(2), D(3), and D(4)) receptor signaling invo...

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Detalhes bibliográficos
Main Authors: Ramadan, Epolia, Basselin, Mireille, Taha, Ameer Y., Cheon, Yewon, Chang, Lisa, Chen, Mei, Rapoport, Stanley I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190603/
https://ncbi.nlm.nih.gov/pubmed/21839100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.07.025
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