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The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma

Renal cell carcinoma (RCC) is the most common form of kidney cancer. While cure remains exceptionally infrequent in RCC patients with systemic or recurrent disease, current targeted molecular strategies, including multi-targeted tyrosine kinase inhibitors (TKIs), notably changed the treatment paradi...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Makhov, Peter, Naito, Sei, Haifler, Miki, Kutikov, Alexander, Boumber, Yanis, Uzzo, Robert G., Kolenko, Vladimir M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841329/
https://ncbi.nlm.nih.gov/pubmed/29515108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0388-1
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