Loading...

CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma

BACKGROUND: Multi-targeted tyrosine kinase inhibitors (TKIs) are the standard of care for patients with advanced clear cell renal cell carcinoma (ccRCC). However, a significant number of ccRCC patients are primarily refractory to targeted therapeutics, showing neither disease stabilisation nor clini...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Makhov, Peter, Sohn, Ji A., Serebriiskii, Ilya G., Fazliyeva, Rushaniya, Khazak, Vladimir, Boumber, Yanis, Uzzo, Robert G., Kolenko, Vladimir M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723036/
https://ncbi.nlm.nih.gov/pubmed/32968206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01087-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!