The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma

Renal cell carcinoma (RCC) is the most common form of kidney cancer. While cure remains exceptionally infrequent in RCC patients with systemic or recurrent disease, current targeted molecular strategies, including multi-targeted tyrosine kinase inhibitors (TKIs), notably changed the treatment paradi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Makhov, Peter, Naito, Sei, Haifler, Miki, Kutikov, Alexander, Boumber, Yanis, Uzzo, Robert G., Kolenko, Vladimir M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841329/
https://ncbi.nlm.nih.gov/pubmed/29515108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0388-1
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