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Piperlongumine Inhibits NF-κB Activity and Attenuates Aggressive Growth Characteristics of Prostate Cancer Cells

BACKGROUND: Elevated NF-κB activity has been previously demonstrated in prostate cancer cell lines as hormone-independent or metastatic characteristics develop. We look at the effects of piperlongumine (PL), a biologically active alkaloid/amide present in piper longum plant, on the NF-κB pathway in...

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Detalhes bibliográficos
Main Authors: Ginzburg, Serge, Golovine, Konstantin V., Makhov, Petr B., Uzzo, Robert G., Kutikov, Alexander, Kolenko, Vladimir M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052841/
https://ncbi.nlm.nih.gov/pubmed/24151226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22739
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