Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-κB-independent, proteasome-mediated mechanism

BACKGROUND: Cadmium has been classified as a human carcinogen, affecting health through occupational and environmental exposure. Cadmium has a long biological half-life (>25 years), due to the flat kinetics of its excretion. The prostate is one of the organs with highest levels of cadmium accumul...

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Main Authors: Golovine, Konstantin, Makhov, Peter, Uzzo, Robert G, Kutikov, Alexander, Kaplan, David J, Fox, Eric, Kolenko, Vladimir M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044330/
https://ncbi.nlm.nih.gov/pubmed/20618956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-183
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