Overexpression of the zinc uptake transporter hZIP1 inhibits NF-κB and reduces the malignant potential of prostate cancer cells in vitro and in vivo

Por Golovine, Konstantin, Makhov, Peter, Uzzo, Robert G., Shaw, Tavis, Kunkle, David, Kolenko, Vladimir M.
Publicado em 2008

Depletion of intracellular zinc increases expression of tumorigenic cytokines VEGF, IL-6 and IL-8 in prostate cancer cells via NF-κB dependent pathway

Por Golovine, Konstantin, Uzzo, Robert G., Makhov, Peter, Crispen, Paul L., Kunkle, David, Kolenko, Vladimir M.
Publicado em 2008

Transcriptional regulation of the major zinc uptake protein hZip1 in prostate cancer cells

Por Makhov, Peter, Golovine, Konstantin, Uzzo, Robert G., Wuestefeld, Torsten, Scoll, Benjamin J., Kolenko, Vladimir M.
Publicado em 2008

Docetaxel-mediated Apoptosis in Myeloid Progenitor TF-1 Cells is Mitigated by Zinc: Potential Implication for Prostate Cancer Therapy

Por Makhov, Peter, Kutikov, Alexander, Golovine, Konstantin, Uzzo, Robert G., Canter, Daniel J., Kolenko, Vladimir M.
Publicado em 2011

Are All Multi-targeted Tyrosine Kinase Inhibitors Created Equal? An In Vitro Study of Sunitinib and Pazopanib in Renal Cell Carcinoma Cell Lines

Por Canter, Daniel, Kutikov, Alexander, Golovine, Konstantin, Makhov, Petr, Simhan, Jay, Uzzo, Robert G., Kolenko, Vladimir M.
Publicado em 2011

Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells

Por Golovine, Konstantin, Makhov, Peter, Teper, Ervin, Kutikov, Alexander, Canter, Daniel, Uzzo, Robert G., Kolenko, Vladimir M.
Publicado em 2012

Piperlongumine Inhibits NF-κB Activity and Attenuates Aggressive Growth Characteristics of Prostate Cancer Cells

Por Ginzburg, Serge, Golovine, Konstantin V., Makhov, Petr B., Uzzo, Robert G., Kutikov, Alexander, Kolenko, Vladimir M.
Publicado em 2013

Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-κB-independent, proteasome-mediated mechanism

Por Golovine, Konstantin, Makhov, Peter, Uzzo, Robert G, Kutikov, Alexander, Kaplan, David J, Fox, Eric, Kolenko, Vladimir M
Publicado em 2010

Co-Administration of Piperine and Docetaxel Results in Improved Anti-Tumor Efficacy via Inhibition of CYP3A4 Activity

Por Makhov, Peter, Golovine, Konstantin, Canter, Daniel, Kutikov, Alexander, Simhan, Jay, Corlew, Melany M., Uzzo, Robert G., Kolenko, Vladimir M.
Publicado em 2011

Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis (XIAP) and sensitizes prostate cancer cells to TRAIL-mediated apoptosis

Por Makhov, Peter, Golovine, Konstantin, Uzzo, Robert G., Rothman, Jason, Crispen, Paul L., Shaw, Tavis, Scoll, Benjamin J., Kolenko, Vladimir M.
Publicado em 2008

Interleukin-6: A Potential Biomarker of Resistance to Multitargeted Receptor Tyrosine Kinase Inhibitors in Castration-Resistant Prostate Cancer

Por Kutikov, Alexander, Makhov, Peter, Golovine, Konstantin, Canter, Daniel J., Sirohi, Mohit, Street, Ryan, Simhan, Jay, Uzzo, Robert G., Kolenko, Vladimir M.
Publicado em 2011

Minor grove binding ligands disrupt PARP-1 activation pathways

Por Kirsanov, Kirill I., Kotova, Elena, Makhov, Petr, Golovine, Konstantin, Lesovaya, Ekaterina A., Kolenko, Vladimir M., Yakubovskaya, Marianna G., Tulin, Alexei V.
Publicado em 2014

Piperlongumine and its analogs down-regulate expression of c-Met in renal cell carcinoma

Por Golovine, Konstantin, Makhov, Peter, Naito, Sei, Raiyani, Henish, Tomaszewski, Jeffrey, Mehrazin, Reza, Tulin, Alexei, Kutikov, Alexander, Uzzo, Robert G, Kolenko, Vladimir M
Publicado no Cancer Biol Ther (2015)

The Effect of 5-Aminolevulinic Acid and its Derivatives on Protoporphyrin IX Accumulation and Apoptotic Cell Death in Castrate-Resistant Prostate Cancer Cells

Por Teper, Ervin, Makhov, Peter, Golovine, Konstantin, Canter, Daniel J., Myers, Cynthia B., Kutikov, Alexander, Sterious, Steven N., Uzzo, Robert G., Kolenko, Vladimir M.
Publicado em 2012

Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells

Por Makhov, Peter B., Golovine, Konstantin V., Kutikov, Alexander, Canter, Daniel J., Rybko, Vera A., Roshchin, Dmitry A., Matveev, Vsevolod B., Uzzo, Robert G., Kolenko, Vladimir M.
Publicado em 2011