The Effect of 5-Aminolevulinic Acid and its Derivatives on Protoporphyrin IX Accumulation and Apoptotic Cell Death in Castrate-Resistant Prostate Cancer Cells

OBJECTIVE: To examine whether pharmacologically relevant zinc-binding agents are capable of depleting XIAP in tumor cells. Our prior work reveals that treatment with zinc chelating agents induces selective down-regulation of the X-linked inhibitor of apoptosis protein (XIAP) in cancer cells of vario...

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Detalhes bibliográficos
Main Authors: Teper, Ervin, Makhov, Peter, Golovine, Konstantin, Canter, Daniel J., Myers, Cynthia B., Kutikov, Alexander, Sterious, Steven N., Uzzo, Robert G., Kolenko, Vladimir M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514607/
https://ncbi.nlm.nih.gov/pubmed/22950992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2012.07.008
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