Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells

BACKGROUND: Androgen receptor (AR) signaling is regarded as the driving force in prostate carcinogenesis, and its modulation represents a logical target for prostate cancer (PC) prevention and treatment. Natural products are the most consistent source of small molecules for drug development. In this...

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Главные авторы: Golovine, Konstantin, Makhov, Peter, Teper, Ervin, Kutikov, Alexander, Canter, Daniel, Uzzo, Robert G., Kolenko, Vladimir M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491117/
https://ncbi.nlm.nih.gov/pubmed/22592999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22535
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