Leukotriene D(4) and prostaglandin E(2) signals synergize and potentiate vascular inflammation in a mast cell–dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3

BACKGROUND: Although arachidonic acid metabolites, cysteinyl leukotrienes (cys-LTs; leukotriene [LT] C(4), LTD(4), and LTE(4)), and prostaglandin (PG) E(2) are generated at the site of inflammation, it is not known whether crosstalk exists between these 2 classes of inflammatory mediators. OBJECTIVE...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Allergy Clin Immunol
Prif Awduron: Kondeti, Vinay, Al-Azzam, Nosayba, Duah, Ernest, Thodeti, Charles K., Boyce, Joshua A., Paruchuri, Sailaja
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839097/
https://ncbi.nlm.nih.gov/pubmed/26255103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.06.030
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