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Differential Regulation of Cysteinyl Leukotriene Receptor Signaling by Protein Kinase C in Human Mast Cells

Cysteinyl leukotrienes (cys-LTs) are a group of lipid mediators that are potent bronchoconstrictors, powerful inducers of vascular leakage and potentiators of airway hyperresponsiveness. Cys-LTs play an essential role in asthma and are synthesized as well as activated in mast cells (MCs). Cys-LTs re...

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Autors principals: Kondeti, Vinay, Duah, Ernest, Al-Azzam, Nosayba, Thodeti, Charles K., Boyce, Joshua A., Paruchuri, Sailaja
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744564/
https://ncbi.nlm.nih.gov/pubmed/23977066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071536
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