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Cysteinyl leukotrienes regulate endothelial cell inflammatory and proliferative signals through CysLT(2) and CysLT(1) receptors
Cysteinyl leukotrienes (cys-LTs), LTC(4), LTD(4), LTE(4) are potent inflammatory lipid mediators that act through two distinct G-protein-coupled receptors, CysLT(1)R and CysLT(2)R. Although cys-LTs are shown to induce vascular leakage and atherosclerosis, the molecular mechanism by which cys-LTs mod...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834363/ https://ncbi.nlm.nih.gov/pubmed/24253666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03274 |
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