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Modulation of mast cell proliferative and inflammatory responses by Leukotriene D(4) and Stem Cell Factor signaling interactions

Mast cells (MCs) are important effector cells in asthma and pulmonary inflammation, and their proliferation and maturation is maintained by stem cell factor (SCF) via its receptor, c-Kit. Cysteinyl leukotrienes (cys-LTs) are potent inflammatory mediators that signal through CysLT(1)R and CysLT(2)R l...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Al-Azzam, Nosayba, Kondeti, Vinay, Duah, Ernest, Gombedza, Farai, Thodeti, Charles K., Paruchuri, Sailaja
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244248/
https://ncbi.nlm.nih.gov/pubmed/25161061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24777
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