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Modulation of mast cell proliferative and inflammatory responses by Leukotriene D(4) and Stem Cell Factor signaling interactions

Mast cells (MCs) are important effector cells in asthma and pulmonary inflammation, and their proliferation and maturation is maintained by stem cell factor (SCF) via its receptor, c-Kit. Cysteinyl leukotrienes (cys-LTs) are potent inflammatory mediators that signal through CysLT(1)R and CysLT(2)R l...

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Bibliografske podrobnosti
izdano v:J Cell Physiol
Main Authors: Al-Azzam, Nosayba, Kondeti, Vinay, Duah, Ernest, Gombedza, Farai, Thodeti, Charles K., Paruchuri, Sailaja
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244248/
https://ncbi.nlm.nih.gov/pubmed/25161061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24777
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