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Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells
Immune checkpoint inhibition has been shown to successfully reactivate endogenous T cell responses directed against tumor-associated antigens, resulting in significantly prolonged overall survival in patients with various tumor entities. For malignancies with low endogenous immune responses, this ap...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835137/ https://ncbi.nlm.nih.gov/pubmed/29535740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00385 |
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