T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment

BACKGROUND: T cell function is crucial for the success of several novel immunotherapeutic strategies for the treatment of acute myeloid leukemia (AML). However, changes in phenotype and function of T cells have been described in various hematologic malignancies, mimicking T cell exhaustion known fro...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Hematol Oncol
Autors principals: Schnorfeil, Frauke M., Lichtenegger, Felix S., Emmerig, Katharina, Schlueter, Miriam, Neitz, Julia S., Draenert, Rika, Hiddemann, Wolfgang, Subklewe, Marion
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518596/
https://ncbi.nlm.nih.gov/pubmed/26219463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0189-2
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars