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Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells
Immune checkpoint inhibition has been shown to successfully reactivate endogenous T cell responses directed against tumor-associated antigens, resulting in significantly prolonged overall survival in patients with various tumor entities. For malignancies with low endogenous immune responses, this ap...
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| Publicat a: | Front Immunol |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835137/ https://ncbi.nlm.nih.gov/pubmed/29535740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00385 |
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