Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells

Immune checkpoint inhibition has been shown to successfully reactivate endogenous T cell responses directed against tumor-associated antigens, resulting in significantly prolonged overall survival in patients with various tumor entities. For malignancies with low endogenous immune responses, this ap...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Immunol
Hlavní autoři: Lichtenegger, Felix S., Rothe, Maurine, Schnorfeil, Frauke M., Deiser, Katrin, Krupka, Christina, Augsberger, Christian, Schlüter, Miriam, Neitz, Julia, Subklewe, Marion
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835137/
https://ncbi.nlm.nih.gov/pubmed/29535740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00385
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky