Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Pyruvate kinase M2 (PKM2) is a glycolytic enzyme that is expressed in cancer cells. Its role in tumor metabolism is not definitively established, but investigators have suggested that regulation of PKM2 activity can cause accumulation of glycolytic intermediates and increase flux through the pentose...

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Опубликовано в: :Cell Death Dis
Главные авторы: Rajala, Ammaji, Wang, Yuhong, Brush, Richard S., Tsantilas, Kristine, Jankowski, Connor S. R., Lindsay, Ken J., Linton, Jonathan D., Hurley, James B., Anderson, Robert E., Rajala, Raju V. S.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833680/
https://ncbi.nlm.nih.gov/pubmed/29445082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0296-4
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