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The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina

The tumor form of pyruvate kinase M2 (PKM2) undergoes tyrosine phosphorylation and gives rise to the Warburg effect. The Warburg effect defines a pro-oncogenic metabolism switch such that cancer cells take up more glucose than normal tissue and favor incomplete oxidation of glucose, even in the pres...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rajala, Raju V. S., Rajala, Ammaji, Kooker, Christopher, Wang, Yuhong, Anderson, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121888/
https://ncbi.nlm.nih.gov/pubmed/27883057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37727
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