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The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina
The tumor form of pyruvate kinase M2 (PKM2) undergoes tyrosine phosphorylation and gives rise to the Warburg effect. The Warburg effect defines a pro-oncogenic metabolism switch such that cancer cells take up more glucose than normal tissue and favor incomplete oxidation of glucose, even in the pres...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5121888/ https://ncbi.nlm.nih.gov/pubmed/27883057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37727 |
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