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The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina

The tumor form of pyruvate kinase M2 (PKM2) undergoes tyrosine phosphorylation and gives rise to the Warburg effect. The Warburg effect defines a pro-oncogenic metabolism switch such that cancer cells take up more glucose than normal tissue and favor incomplete oxidation of glucose, even in the pres...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Rajala, Raju V. S., Rajala, Ammaji, Kooker, Christopher, Wang, Yuhong, Anderson, Robert E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121888/
https://ncbi.nlm.nih.gov/pubmed/27883057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37727
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