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The p110α Isoform of Phosphoinositide 3-Kinase is Essential for Cone Photoreceptor Survival

Phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases that phosphorylates the 3'OH of the inositol ring of phosphoinositides (PIs). They are responsible for coordinating a diverse range of cellular functions. Class IA PI3K is a heterodimeric protein composed of a regulatory p85 and a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochimie
Main Authors: Rajala, Raju V.S., Ranjo-Bishop, Michelle, Wang, Yuhong, Rajala, Ammaji, Anderson, Robert E.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402270/
https://ncbi.nlm.nih.gov/pubmed/25742742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2015.02.018
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