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Constitutive Activation Mutant mTOR Promote Cone Survival in Retinitis Pigmentosa mice

Studies form our laboratory and others show that the oncogenic tyrosine kinase and serine threonine kinase signaling pathways are essential for cone photoreceptor survival. These pathways are downregulated in mouse models of retinal degenerative diseases. In the present study, we found that activati...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Rajala, Ammaji, Wang, Yuhong, Rajala, Raju V.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424566/
https://ncbi.nlm.nih.gov/pubmed/29721981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-75402-4_61
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