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Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of Retinitis Pigmentosa

Retinitis Pigmentosa (RP) is an incurable retinal disease that leads to blindness. One puzzling aspect concerns the progression of the disease. While most mutations that cause RP are in rod photoreceptor (PR) -specific genes, cone PRs die as well. To understand the mechanism of non-autonomous cone d...

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Detalhes bibliográficos
Main Authors: Punzo, Claudio, Kornacker, Karl, Cepko, Constance L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339764/
https://ncbi.nlm.nih.gov/pubmed/19060896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2234
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