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Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of Retinitis Pigmentosa

Retinitis Pigmentosa (RP) is an incurable retinal disease that leads to blindness. One puzzling aspect concerns the progression of the disease. While most mutations that cause RP are in rod photoreceptor (PR) -specific genes, cone PRs die as well. To understand the mechanism of non-autonomous cone d...

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Hlavní autoři: Punzo, Claudio, Kornacker, Karl, Cepko, Constance L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339764/
https://ncbi.nlm.nih.gov/pubmed/19060896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2234
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