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Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival

In humans, daylight vision is primarily mediated by cone photoreceptors. These cells die in age-related retinal degenerations. Prolonging the life of cones for even one decade would have an enormous beneficial effect on usable vision in an aging population. Photoreceptors are postmitotic, but shed 1...

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Vydáno v:Oncotarget
Hlavní autoři: Rajala, Ammaji, Wang, Yuhong, Rajala, Raju V.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216914/
https://ncbi.nlm.nih.gov/pubmed/27391439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10447
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