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Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival

In humans, daylight vision is primarily mediated by cone photoreceptors. These cells die in age-related retinal degenerations. Prolonging the life of cones for even one decade would have an enormous beneficial effect on usable vision in an aging population. Photoreceptors are postmitotic, but shed 1...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Rajala, Ammaji, Wang, Yuhong, Rajala, Raju V.S.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216914/
https://ncbi.nlm.nih.gov/pubmed/27391439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10447
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