Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Pyruvate kinase M2 (PKM2) is a glycolytic enzyme that is expressed in cancer cells. Its role in tumor metabolism is not definitively established, but investigators have suggested that regulation of PKM2 activity can cause accumulation of glycolytic intermediates and increase flux through the pentose...

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Pubblicato in:Cell Death Dis
Autori principali: Rajala, Ammaji, Wang, Yuhong, Brush, Richard S., Tsantilas, Kristine, Jankowski, Connor S. R., Lindsay, Ken J., Linton, Jonathan D., Hurley, James B., Anderson, Robert E., Rajala, Raju V. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833680/
https://ncbi.nlm.nih.gov/pubmed/29445082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0296-4
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