How does temperature impact the conformation of single DNA molecules below melting temperature?

The double stranded DNA molecule undergoes drastic structural changes during biological processes such as transcription during which it opens locally under the action of RNA polymerases. Local spontaneous denaturation could contribute to this mechanism by promoting it. Supporting this idea, differen...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Brunet, Annaël, Salomé, Laurence, Rousseau, Philippe, Destainville, Nicolas, Manghi, Manoel, Tardin, Catherine
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829751/
https://ncbi.nlm.nih.gov/pubmed/29294104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1285
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