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How does temperature impact the conformation of single DNA molecules below melting temperature?

The double stranded DNA molecule undergoes drastic structural changes during biological processes such as transcription during which it opens locally under the action of RNA polymerases. Local spontaneous denaturation could contribute to this mechanism by promoting it. Supporting this idea, differen...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Brunet, Annaël, Salomé, Laurence, Rousseau, Philippe, Destainville, Nicolas, Manghi, Manoel, Tardin, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829751/
https://ncbi.nlm.nih.gov/pubmed/29294104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1285
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