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How does temperature impact the conformation of single DNA molecules below melting temperature?

The double stranded DNA molecule undergoes drastic structural changes during biological processes such as transcription during which it opens locally under the action of RNA polymerases. Local spontaneous denaturation could contribute to this mechanism by promoting it. Supporting this idea, differen...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Brunet, Annaël, Salomé, Laurence, Rousseau, Philippe, Destainville, Nicolas, Manghi, Manoel, Tardin, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829751/
https://ncbi.nlm.nih.gov/pubmed/29294104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1285
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