How does temperature impact the conformation of single DNA molecules below melting temperature?

The double stranded DNA molecule undergoes drastic structural changes during biological processes such as transcription during which it opens locally under the action of RNA polymerases. Local spontaneous denaturation could contribute to this mechanism by promoting it. Supporting this idea, differen...

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Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Brunet, Annaël, Salomé, Laurence, Rousseau, Philippe, Destainville, Nicolas, Manghi, Manoel, Tardin, Catherine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829751/
https://ncbi.nlm.nih.gov/pubmed/29294104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1285
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