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High-throughput single-molecule analysis of DNA–protein interactions by tethered particle motion
Tethered particle motion (TPM) monitors the variations in the effective length of a single DNA molecule by tracking the Brownian motion of a bead tethered to a support by the DNA molecule. Providing information about DNA conformations in real time, this technique enables a refined characterization o...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384352/ https://ncbi.nlm.nih.gov/pubmed/22422843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks250 |
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