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High-throughput single-molecule analysis of DNA–protein interactions by tethered particle motion

Tethered particle motion (TPM) monitors the variations in the effective length of a single DNA molecule by tracking the Brownian motion of a bead tethered to a support by the DNA molecule. Providing information about DNA conformations in real time, this technique enables a refined characterization o...

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Autori principali: Plénat, Thomas, Tardin, Catherine, Rousseau, Philippe, Salomé, Laurence
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384352/
https://ncbi.nlm.nih.gov/pubmed/22422843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks250
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