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Physical constraints in polymer modeling of chromatin associations with the nuclear periphery at kilobase scale

Interactions of chromatin with the nuclear lamina imposes a radial genome distribution important for nuclear functions. How physical properties of chromatin affect these interactions is unclear. We used polymer simulations to model how physical parameters of chromatin affect its interaction with the...

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Détails bibliographiques
Publié dans:Nucleus
Auteurs principaux: Brunet, Annaël, Destainville, Nicolas, Collas, Philippe
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808377/
https://ncbi.nlm.nih.gov/pubmed/33435761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2020.1868105
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