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How does temperature impact the conformation of single DNA molecules below melting temperature?

The double stranded DNA molecule undergoes drastic structural changes during biological processes such as transcription during which it opens locally under the action of RNA polymerases. Local spontaneous denaturation could contribute to this mechanism by promoting it. Supporting this idea, differen...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Brunet, Annaël, Salomé, Laurence, Rousseau, Philippe, Destainville, Nicolas, Manghi, Manoel, Tardin, Catherine
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829751/
https://ncbi.nlm.nih.gov/pubmed/29294104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1285
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