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Three classes of recurrent DNA break clusters in brain progenitors identified by 3D proximity-based break joining assay
We recently discovered 27 recurrent DNA double-strand break (DSB) clusters (RDCs) in mouse neural stem/progenitor cells (NSPCs). Most RDCs occurred across long, late-replicating RDC genes and were found only after mild inhibition of DNA replication. RDC genes share intriguing characteristics, includ...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828622/ https://ncbi.nlm.nih.gov/pubmed/29432181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719907115 |
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