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Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture

Mild replication stress enhances appearance of dozens of robust recurrent genomic break clusters, termed RDCs, in cultured primary mouse neural stem and progenitor cells (NSPCs). Robust RDCs occur within genes (“RDC-genes”) that are long and have roles in neural cell communications and/or have been...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tena, Aseda, Zhang, Yuxiang, Kyritsis, Nia, Devorak, Anne, Zurita, Jeffrey, Wei, Pei-Chi, Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229678/
https://ncbi.nlm.nih.gov/pubmed/32332169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922299117
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