Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture

Mild replication stress enhances appearance of dozens of robust recurrent genomic break clusters, termed RDCs, in cultured primary mouse neural stem and progenitor cells (NSPCs). Robust RDCs occur within genes (“RDC-genes”) that are long and have roles in neural cell communications and/or have been...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tena, Aseda, Zhang, Yuxiang, Kyritsis, Nia, Devorak, Anne, Zurita, Jeffrey, Wei, Pei-Chi, Alt, Frederick W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229678/
https://ncbi.nlm.nih.gov/pubmed/32332169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922299117
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